MEM-DR516L-CL01-ER48 Supermicro 16GB Pc5-38400 DDR5 Ecc Registered 1rx8 Cl40 SDRAM 288-Pin 1.1v Dimm Memory

Highlights of Supermicro MEM-DR516L-CL01-ER48 16GB Memory

The Supermicro MEM-DR516L-CL01-ER48 is a reliable and efficient DDR5 RDIMM memory module engineered for enterprise-grade servers. With a speed of 4800MHz, ECC support, and registered architecture, this 16GB DIMM delivers stable performance for data-intensive workloads, virtualization, and cloud computing environments.

General Information 

• Manufacturer: Supermicro
• Part Number: MEM-DR516L-CL01-ER48
• Product Type: Memory Module
• Sub Type: DDR5 4800MHz SDRAM  PC5-38400

Technical Specifications

• Capacity: 16GB
• Rank: Single Rank (1Rx8)
• Memory Speed: DDR5-4800 / PC5-38400
• CAS Latency: CL40
• ECC Support: Detects and corrects data errors
• Registered Module: Reduces electrical load
• Voltage: 1.1V low-power operation

Physical Characteristics

Form Factor & Dimensions

• Form Factor: 288-Pin DIMM
• Module Type: RDIMM (Registered DIMM)

Compatibility

Supported Servers & CPUs

• Supermicro X13 series servers and newer platforms with DDR5 support
• 4th Gen Intel® Xeon® Scalable processors (Sapphire Rapids)
• AMD EPYC™ 9004 series (Genoa) servers that support DDR5-4800 RDIMM modules

Memory Slot & BIOS Requirements

• Requires standard 288-pin RDIMM slots on compatible server motherboards
• Only compatible with servers that support ECC Registered DDR5 modules
• BIOS updates may be required for proper recognition of DDR5 memory

Overview of Supermicro MEM-DR516L-CL01-ER48 16GB DDR5

The Supermicro MEM-DR516L-CL01-ER48 16GB DDR5-4800MHz PC5-38400 ECC Registered 1Rx8 CL40 SDRAM 288-Pin 1.1v DIMM memory module represents a cutting-edge category of enterprise-grade server memory engineered to meet the performance, reliability, and scalability requirements of modern data centers and enterprise servers. This category focuses on high-efficiency DDR5 modules with moderate capacity, designed to provide dependable performance across a variety of workloads, from virtualization and cloud computing to real-time analytics and mission-critical enterprise applications. The MEM-DR516L-CL01-ER48 modules are built with ECC (Error-Correcting Code) technology and a registered DIMM design, ensuring the stability and reliability that enterprise environments demand while supporting large-scale server deployments with optimal memory performance.

DDR5-4800MHz Performance and Bandwidth

The MEM-DR516L-CL01-ER48 category operates at 4800MHz, offering substantial improvements over DDR4 memory in both bandwidth and data throughput. With a PC5-38400 bandwidth rating, these modules are capable of transferring large volumes of data rapidly between the memory and the CPU, which is essential for workloads that require fast access to memory resources. Enterprise applications such as virtualization, in-memory databases, and cloud-based workloads benefit from the enhanced throughput, which reduces latency and improves overall server responsiveness. The high frequency ensures that multiple memory-intensive processes can run concurrently without creating bottlenecks, allowing servers to maintain peak efficiency even under heavy computational or I/O demands.

16GB Capacity for Flexible Server Deployment

A central feature of the MEM-DR516L-CL01-ER48 memory category is its 16GB capacity per DIMM. This capacity is designed to provide a flexible and cost-efficient solution for a wide variety of server workloads without the need for extremely high-capacity modules. 16GB modules are ideal for mid-tier servers, virtualization nodes, web servers, and application servers where moderate to high memory throughput is required. Enterprises can achieve scalable configurations by combining multiple 16GB modules across available DIMM slots, allowing for increased total memory while maintaining a predictable and manageable system design.

ECC and Registered DIMM Reliability

Reliability is a defining attribute of the MEM-DR516L-CL01-ER48 category. These modules incorporate ECC technology to detect and correct single-bit memory errors, reducing the risk of data corruption, system crashes, and unplanned downtime. ECC memory is critical in enterprise servers where mission-critical applications, financial databases, and cloud workloads require high availability and precise data integrity. By using ECC, this category ensures consistent memory reliability even under demanding workloads and continuous operation, making it suitable for enterprise and data center environments where uptime is essential.

1Rx8 Single-Rank Memory Configuration

The MEM-DR516L-CL01-ER48 modules utilize a 1Rx8 single-rank architecture, meaning data is distributed across a single rank of x8 DRAM chips. This configuration provides efficient memory utilization and compatibility with a wide range of server systems. Single-rank modules are often preferred for workloads that benefit from higher memory channel efficiency and lower latency in certain multi-DIMM configurations. The x8 organization also contributes to robust ECC error handling, ensuring that each memory operation maintains data integrity and reduces the likelihood of errors in enterprise environments.

288-Pin DDR5 Form Factor

The MEM-DR516L-CL01-ER48 modules adhere to the standard 288-pin DDR5 form factor, ensuring compatibility with modern server motherboards designed to support DDR5 memory. This standardization enables IT professionals to deploy these modules across multiple server platforms without concerns about physical or electrical incompatibilities. The 288-pin design supports high-speed signaling, stable voltage delivery, and efficient thermal dissipation, all of which are essential for maintaining reliable memory performance in enterprise servers. Compatibility with multiple server platforms simplifies inventory management, reduces deployment complexity, and ensures that these modules can be integrated into diverse IT environments.

Supermicro Server Platforms

This memory category is validated for use in Supermicro enterprise servers, ensuring that each module operates reliably under the recommended voltage, timing, and thermal conditions. Validation testing provides assurance that servers equipped with MEM-DR516L-CL01-ER48 modules will maintain consistent performance under sustained workloads. While optimized for Supermicro platforms, these DDR5 modules are generally compatible with other server systems that support DDR5 RDIMM specifications, although system-level verification is recommended to maximize performance and reliability.

Scalability for Enterprise Workloads

One of the primary advantages of the MEM-DR516L-CL01-ER48 category is its scalability. IT administrators can deploy multiple 16GB modules to build flexible server configurations, enabling vertical and horizontal scaling for virtualization, cloud computing, in-memory analytics, and enterprise applications. This memory category supports predictable performance across multiple DIMM slots and multi-socket configurations, ensuring that memory-intensive applications can scale without compromising stability or reliability.

Enterprise and Data Center Applications

The MEM-DR516L-CL01-ER48 category is suitable for a wide range of enterprise and data center workloads. In virtualization environments, multiple 16GB modules allow higher virtual machine density, improved memory allocation, and enhanced overall server performance. For database-intensive applications, these modules provide adequate in-memory cache and fast data access, reducing reliance on slower storage and improving transaction processing times. Cloud computing workloads, web servers, and AI or analytics applications benefit from the combination of DDR5 speed, moderate capacity, and ECC reliability, which ensures consistent, uninterrupted operation in mission-critical environments.

Machine Learning and HPC

While higher-capacity memory modules are often preferred for large-scale AI and HPC tasks, 16GB DDR5 modules in this category provide sufficient memory bandwidth and stability to support distributed AI workloads, smaller training datasets, and edge computing scenarios. The DDR5-4800MHz speed ensures that servers can process data efficiently across multiple cores, while ECC protection minimizes the risk of memory errors during extended computations. Multi-server clusters using this memory category can scale horizontally to handle larger datasets and high-performance workloads.

Data Center and Cloud Infrastructure

For enterprise cloud and data center deployments, the MEM-DR516L-CL01-ER48 category enables predictable and cost-effective memory scaling. Data centers can leverage 16GB DDR5 modules to configure virtualized nodes, web hosting servers, or application clusters with consistent memory performance. Standardized module capacity reduces configuration errors, simplifies inventory, and ensures reliable operation across heterogeneous server environments. Enterprises gain the flexibility to deploy memory where needed while maintaining operational efficiency and high service availability.

Long-Term Reliability and Validation

Supermicro validates this memory category for long-term operation under demanding server workloads, ensuring that performance remains consistent, failure rates are minimized, and uptime is maximized. The combination of ECC, RDIMM architecture, and industry-standard DDR5 testing ensures that the MEM-DR516L-CL01-ER48 modules meet the reliability expectations of enterprise-grade deployments, including financial systems, cloud infrastructure, and mission-critical IT environments.

DDR5 Memory Investment

Investing in DDR5 memory modules such as the MEM-DR516L-CL01-ER48 category positions enterprises to adopt future-ready server hardware capable of supporting next-generation workloads. This category delivers a balance of speed, reliability, and efficiency while maintaining compatibility with emerging server platforms. The 16GB modules provide sufficient capacity for most mid-tier workloads today while enabling incremental upgrades as memory demands increase in the future, ensuring a cost-effective and long-term memory solution.

Integration with Advanced Server Chipsets

Modern server chipsets are designed to optimize DDR5 memory capabilities, including higher channel counts, improved memory interleaving, and advanced error detection mechanisms. MEM-DR516L-CL01-ER48 modules integrate seamlessly with these chipsets to deliver consistent bandwidth, low latency, and stable performance. This integration ensures balanced system operation across CPUs, memory, and I/O subsystems, supporting enterprise workloads that demand predictable, high-performance memory behavior.

Standardization and Deployment

Standardizing memory modules across servers simplifies procurement, deployment, and maintenance. The MEM-DR516L-CL01-ER48 category provides consistent specifications, enabling IT teams to maintain predictable memory performance, reduce configuration errors, and simplify system upgrades. Standardized deployment ensures that servers operate efficiently across multi-node environments and that future scaling or replacement of modules can be done without compatibility concerns.