P69728-K21 HPE 64GB Dual Rank X4 Ddr5-6400MT/s PC5-51200 Memory.

HPE P69728-K21 64GB DDR5-6400MT/s Memory Overview

The HPE P69728-K21 64GB Dual Rank x4 DDR5-6400MT/s PC5-51200 Server Memory represents the next-generation upgrade for enterprise-grade systems demanding maximum bandwidth, lower power consumption, and optimized performance. As part of Hewlett Packard Enterprise’s industry-leading server memory lineup, this memory module ensures uncompromising reliability and stability under the most intensive workloads.

High-Speed Performance with DDR5-6400MT/s

This memory module operates at a lightning-fast 6400 mega transfers per second (MT/s), offering significantly improved data rates compared to DDR4. With its PC5-51200 classification, the HPE P69728-K21 delivers enhanced throughput and higher frequencies ideal for data-intensive applications including high-performance computing (HPC), virtualization, large-scale database management, and AI/ML workloads. This superior speed translates to better application responsiveness and faster processing cycles across diverse enterprise infrastructures.

Advanced Dual Rank x4 Architecture

The dual rank x4 configuration of the HPE P69728-K21 maximizes memory bandwidth by enabling more memory banks to be accessed simultaneously. The x4 DR (Dual Rank) architecture allows better interleaving and higher performance for multi-threaded server applications. This design is particularly beneficial for platforms that support multiple memory channels, unlocking the full potential of modern processors and accelerating system tasks efficiently.

Low Power Consumption and Efficiency Gains

DDR5 memory modules like the HPE P69728-K21 are engineered for efficiency. This 64GB DIMM operates at a lower core voltage compared to DDR4, reducing total power draw across server farms or data centers. The lower voltage requirement directly results in decreased thermal output, allowing for more efficient cooling solutions and improved total cost of ownership (TCO).

Compatibility and System Integration

Designed specifically for HPE ProLiant Gen11 and select Gen10 Plus servers, the P69728-K21 is factory-tested and certified for seamless integration into HPE server platforms. Its plug-and-play capability simplifies installation, ensuring that businesses can scale their memory infrastructure without compatibility concerns.

Supported Platforms and Use Cases

This memory module is optimized for the following HPE server families:

• HPE ProLiant DL380 Gen11
• HPE ProLiant DL360 Gen11
• HPE ProLiant ML350 Gen11
• HPE Apollo 6500 Gen10 Plus
• HPE Synergy Gen11 Compute Modules

These systems are commonly deployed in enterprise environments including cloud infrastructure, financial services, healthcare analytics, government operations, scientific research, and data warehousing.

Virtualization and Cloud Computing Advantages

In virtualized environments, having high-speed and high-capacity memory modules is crucial. The 64GB DDR5 module enables greater VM density per host, reducing licensing costs and improving performance. Cloud service providers benefit from reduced overhead, while private data centers can achieve better load balancing and fault tolerance.

Scalability for Growing Workloads

As business demands evolve, the need for scalable memory solutions becomes critical. The HPE P69728-K21 64GB DIMM provides the scalability that modern infrastructures require, supporting advanced memory channel interleaving, high-capacity virtualization clusters, and real-time data analytics at scale. It is an ideal choice for organizations planning long-term server investments with DDR5-ready motherboards.

Registered (Buffered) Memory Functionality

As a Registered DIMM, this memory includes a register between the DRAM modules and the memory controller, ensuring signal integrity and enabling servers to handle larger memory footprints with improved stability. Registered memory is a requirement for most enterprise server boards, ensuring high capacity scaling without compromising reliability.

JEDEC Compliance for Future-Proofing

The HPE P69728-K21 adheres to JEDEC DDR5 specifications, ensuring compatibility with current and future HPE-certified systems. JEDEC compliance guarantees that the module meets stringent performance and durability standards, making it a future-ready investment for IT infrastructure upgrades.

HPE Quality and Manufacturing Standards

All HPE-branded memory modules undergo rigorous qualification processes, including extensive factory testing, validation across multiple workloads, and certification for mission-critical applications. The factory-sealed new condition (FSB) ensures customers receive memory modules that are untouched, original, and secure for enterprise deployment.

HPE’s Three-Year Warranty and Support Ecosystem

Every HPE P69728-K21 module is backed by a robust 3-year limited warranty, ensuring peace of mind and protection against manufacturing defects. In the event of hardware issues, customers benefit from HPE’s global support network, which includes rapid replacements, technical assistance, and comprehensive diagnostics tailored for enterprise IT needs.

HPE Insight Diagnostics and Smart Memory Monitoring

Using Smart Memory technology, HPE servers can intelligently detect and monitor memory module health, firmware versions, and predictive failure rates. This seamless integration allows IT teams to proactively manage infrastructure and minimize unplanned downtime. With Smart Memory compatibility, the P69728-K21 delivers enhanced diagnostics and better operational control.

Secure Supply Chain and Authenticity Assurance

Purchasing HPE factory-sealed memory ensures authenticity and safeguards against counterfeit products. The secure supply chain offers traceability from manufacturing to deployment, a critical factor in government, healthcare, and finance industries where compliance and trust are mandatory.

Key Benefits of Upgrading to DDR5 6400MT/s Memory

• Up to 50% bandwidth increase over DDR4 modules.
• Reduced latency and higher operational frequencies.
• Improved parallelism for multi-core CPUs and complex workloads.
• Lower power consumption and better thermal efficiency.
• Enhanced support for multi-tenant cloud, AI/ML, and edge computing.

Performance Enhancements Across Applications

With DDR5 technology, servers experience faster memory fetch rates and improved data processing. Applications like Microsoft SQL Server, VMware ESXi, SAP HANA, and TensorFlow benefit from larger memory footprints and improved interconnect speed, leading to smoother execution and reduced latency spikes during heavy load periods.

Ideal Buyers and Deployment Scenarios

The HPE P69728-K21 64GB module is tailored for IT professionals, data center administrators, and enterprise architects seeking optimal memory solutions for high-density workloads. It supports mission-critical systems that demand continuous uptime, large-scale data processing, and ultra-low latency. Sectors that benefit include:

• Enterprise IT and Corporate Data Centers
• Telecommunications and Infrastructure Providers
• Research and Academic Supercomputing Labs
• AI/ML Development and Training Clusters
• Financial Services and Real-Time Trading Platforms

Use in Edge and Hybrid Environments

As more businesses transition to hybrid models with edge computing capabilities, memory efficiency becomes a central pillar of performance. This 64GB DDR5 module can be deployed in edge servers and micro data centers where physical space is constrained but workload density is high. The memory’s power efficiency and performance help drive edge analytics, real-time response systems, and IoT integration.

Packaging, Delivery, and Installation

Each HPE P69728-K21 module ships factory-sealed in original OEM packaging. Anti-static protection, shock-resistant materials, and tamper-evident seals ensure safe transit and handling. HPE's certified service partners also offer installation and configuration support to assist with seamless deployment across enterprise infrastructure.

Hot-Swappable and Field-Serviceable Design

Thanks to its hot-swappable and field-serviceable design, the HPE memory module can be installed with minimal disruption to operational workflows. Most HPE ProLiant servers support memory upgrades without the need to power down the system, ensuring continuous availability and reducing maintenance windows.