P73450-0C1 HPE 256GB DDR5-6400MT/s PC5-51200 Cl60 Memory.

HPE P73450-0C1 256GB DDR5-6400MT/s Memory Overview

The HPE P73450-0C1 256GB DDR5-6400MT/s PC5-51200 CL60 Memory module represents the pinnacle of high-performance server memory technology. Specifically engineered to meet the demands of enterprise-level computing, this module combines cutting-edge DDR5 technology, extreme capacity, and blazing-fast speeds with Hewlett Packard Enterprise's renowned reliability. This memory is New In Box (NIB), ensuring it arrives factory-sealed and untouched, ideal for datacenter builds, system upgrades, and mission-critical applications.

Compatibility and Use Cases

The HPE P73450-0C1 256GB DDR5 module is designed for seamless integration with compatible HPE ProLiant Gen11 servers and other high-end enterprise-grade systems that support DDR5 DIMMs. With its massive 256GB capacity per DIMM, it is ideal for applications that demand high bandwidth and large memory footprints, such as:

• Large-scale virtualization and hyperconverged infrastructures
• AI/ML data modeling and neural network training
• In-memory databases such as SAP HANA
• Big data analytics and high-performance computing (HPC)
• Enterprise-grade ERP and CRM applications

Server Compatibility Highlights

While this module is optimized for HPE systems, particularly the ProLiant DL and ML series, it may also be compatible with select third-party systems supporting 256GB DDR5 Registered DIMMs. Always consult the motherboard or system documentation to confirm compatibility before installation.

Use in Mission-Critical Applications

In-Memory Computing

For businesses leveraging in-memory databases like SAP HANA or Oracle Database In-Memory, the HPE P73450-0C1 provides the capacity and speed needed to process large datasets entirely in RAM. This results in near-instantaneous query performance, transaction processing, and real-time analytics capabilities.

Artificial Intelligence and Machine Learning

In AI and ML contexts, where large datasets and rapid iterations are the norm, the speed and density of the P73450-0C1 DDR5 DIMM ensures optimal throughput for neural network training, image recognition, language modeling, and other high-bandwidth computations.

Virtualization and Cloud Infrastructure

High memory density is essential in virtualized environments where multiple virtual machines (VMs) run concurrently. This 256GB DDR5 module enables the consolidation of workloads onto fewer physical machines, reducing hardware costs while increasing efficiency.

Reliability and Quality Assurance

Enterprise-Grade Manufacturing

HPE memory modules undergo rigorous testing and validation to meet the highest standards of quality and reliability. The P73450-0C1 is manufactured using premium-grade components and subjected to quality assurance protocols tailored to enterprise IT infrastructure.

ECC Support for Data Integrity

The Error-Correcting Code (ECC) capabilities in DDR5 memory ensure that transient errors in memory cells are automatically detected and corrected, reducing the risk of data corruption in critical systems.

Long-Term Durability

Designed to operate under sustained workloads and environmental stress, this module offers excellent heat dissipation and operates within enterprise thermal envelopes, helping extend the service life of the DIMM even under demanding conditions.

Packaging: New Sealed in Box (NIB)

This product is classified as “New In Box,” meaning it is factory-sealed and has not been previously opened or used. This guarantees the memory’s authenticity, performance, and condition, offering peace of mind and protection against counterfeit or refurbished components.

Advantages of New In Box (NIB) Hardware

• Guaranteed unused, unopened product straight from the manufacturer
• Original HPE packaging and documentation
• Eligible for HPE warranty or partner warranty programs
• Assurance of compatibility and freshness of components

Energy Efficiency and Power Management

The HPE 256GB DDR5-6400 memory module features a Power Management Integrated Circuit (PMIC) on-die, which optimizes energy usage and ensures precise voltage regulation across the DIMM. Compared to DDR4, this improvement contributes to overall system power efficiency—critical for reducing operational expenses in large-scale deployments.

Lower Total Cost of Ownership (TCO)

Though DDR5 memory has a higher initial cost, its improved performance-per-watt ratio and density reduce the total number of DIMMs needed for high-capacity workloads. This results in lower cooling and power requirements across the datacenter, translating into long-term TCO savings.

Security and Firmware Updates

HPE memory modules support secure firmware updates and verification protocols, helping organizations maintain hardware integrity. This security feature is vital in environments where firmware vulnerabilities can impact the entire stack from hardware to application layers.

Support for Secure Boot and Encryption Features

Combined with secure boot mechanisms and platform-level encryption features, DDR5 modules like the P73450-0C1 provide the hardware backbone for robust data protection strategies.

BIOS/UEFI Configuration Notes

Some systems may require BIOS updates to fully utilize DDR5-6400 speeds or register the full 256GB per DIMM. Consult HPE documentation for platform-specific instructions regarding memory speed settings, channel interleaving, and ECC configuration.

Buy and Pricing Insights

The HPE P73450-0C1 is available through authorized HPE resellers, enterprise IT vendors, and online marketplaces. Pricing can vary based on quantity, availability, and regional distribution. Always verify that the seller is an official HPE partner to ensure warranty eligibility and authenticity.

Volume Discounts for Enterprise Customers

For large-scale IT infrastructure projects, many vendors offer significant discounts when purchasing multiple units. Organizations planning memory refreshes, datacenter expansions, or server rollouts should consider negotiating volume-based pricing.

Pairing with Compatible CPUs

To unlock the full performance of the DDR5-6400 modules, pairing with 4th or 5th Gen Intel Xeon Scalable or AMD EPYC processors is recommended. These platforms offer native DDR5 support and leverage the full bandwidth potential of high-speed memory.

Optimizing Multi-Channel Memory Performance

For best results, populate memory channels symmetrically and balance DIMMs across processors in dual-socket configurations. This ensures optimal interleaving and minimizes latency, maximizing throughput for memory-bound workloads.

Monitoring and Diagnostics

HPE provides software tools like Integrated Lights-Out (iLO), OneView, and System Insight Manager (SIM) for memory health monitoring, diagnostics, and predictive failure alerts. Leveraging these tools helps IT administrators maintain uptime and system reliability.