P11339-001 HPE 10/25GB Dual Port SFP+ Ethernet Adapter.

P11339-001 HPE 10/25GB Dual Port SFP+ MCX4621A-ACAB OCP3 Ethernet Adapter Overview

The P11339-001 HPE 10/25GB Dual Port SFP+ MCX4621A-ACAB OCP3 Ethernet Adapter is a cutting-edge networking solution designed to provide high-speed data connectivity for enterprise-class servers. Supporting 10GbE and 25GbE Ethernet speeds through dual-port SFP+ interfaces, this adapter is engineered for performance, reliability, and scalability in data centers, high-performance computing (HPC), cloud environments, and mission-critical enterprise applications.

Form Factor and Compatibility

The HPE P11339-001 adapter leverages the OCP 3.0 (Open Compute Project) standard, enabling seamless integration with modern HPE ProLiant Gen10 and Gen11 servers. It ensures backward and forward compatibility, making it ideal for hybrid infrastructure upgrades.

Performance and Throughput

Supporting 10 and 25 Gigabit Ethernet, this adapter provides up to 50Gbps of aggregated throughput across both ports. Whether used in high-throughput storage networks or latency-sensitive virtualized workloads, it delivers consistent, low-latency performance under heavy traffic conditions.

Bandwidth Optimization

The adapter includes built-in support for Adaptive Routing, RDMA over Converged Ethernet (RoCE), and Receive Side Scaling (RSS), ensuring optimal traffic distribution across CPU cores. This improves application responsiveness and throughput, particularly in software-defined data centers (SDDCs).

Advanced Networking Protocols

With support for VLAN tagging, jumbo frames, and TSO (TCP Segmentation Offload), the MCX4621A-ACAB offers complete L2/L3 networking functionality. Hardware support for VXLAN and NVGRE tunneling enables secure multi-tenant environments, essential for cloud service providers.

Enterprise Use Cases

Virtualization and Cloud Infrastructure

Designed with cloud-native and virtualized infrastructure in mind, the P11339-001 adapter offers SR-IOV support, allowing virtual machines to directly access hardware resources. This dramatically reduces hypervisor overhead and improves VM-to-VM performance.

Hyper-Converged Infrastructure (HCI)

In HCI deployments, where compute and storage are tightly integrated, low-latency networking is vital. The dual-port 25GbE configuration provides the bandwidth necessary for efficient I/O between nodes and storage subsystems.

High-Performance Computing (HPC)

The MCX4621A-ACAB adapter excels in HPC environments, offering RoCE capabilities and ultra-low-latency packet processing. Scientific simulations, real-time analytics, and machine learning training pipelines benefit from its deterministic performance.

Data Center Networking

Data centers rely on scalable, energy-efficient, and high-bandwidth networking solutions. This adapter’s dual-port configuration allows for high availability and link aggregation, supporting active-active failover and maximizing throughput.

Enhanced Security and Network Visibility

Secure Boot and Firmware Integrity

To meet enterprise security standards, the adapter supports secure firmware updates and digitally signed boot processes. This prevents unauthorized modifications and ensures device integrity from initialization to operation.

Telemetry and Monitoring

Real-time telemetry features provide visibility into link performance, utilization, and error statistics. These capabilities help administrators proactively manage infrastructure and troubleshoot network issues before they escalate.

Isolation and Multi-Tenant Segmentation

With built-in support for network overlays like VXLAN and SR-IOV, this adapter allows segmentation of workloads across secure, isolated environments. This is essential for hosting providers and regulated industries that need multi-tenant networking.

Benefits of Choosing the HPE MCX4621A-ACAB Ethernet Adapter

Energy Efficiency

The adapter’s low-power design contributes to reduced energy consumption in dense server environments. Thermal efficiency helps maintain consistent performance under load while minimizing data center cooling requirements.

Reliability and Uptime

With dual-port redundancy and link failover capabilities, the adapter ensures business continuity. Hot-pluggable SFP+ transceivers and remote firmware update features simplify maintenance without disrupting operations.

Vendor Reliability

As a certified Hewlett Packard Enterprise (HPE) component, the P11339-001 adapter is backed by global support and quality assurance. It is compatible with Insight Management and HPE iLO for complete lifecycle management.

Plug-and-Play Deployment

Installation is straightforward via the OCP 3.0 slot in HPE servers. Once inserted, the server BIOS and operating system recognize the device, simplifying initial configuration.

Driver and OS Support

The MCX4621A-ACAB supports major enterprise operating systems, including Windows Server, Red Hat Enterprise Linux (RHEL), SUSE Linux Enterprise Server (SLES), and VMware ESXi. Drivers and firmware packages are available via HPE’s support portal.

Integration with Network Management Tools

Administrators can configure, monitor, and update the adapter through command-line tools, web-based interfaces, and orchestration platforms such as Ansible or HPE OneView, facilitating integration into automated environments.

Transceiver and DAC Cable Compatibility

The adapter supports a wide array of HPE-branded and industry-standard SFP+ and SFP28 optical transceivers, as well as Direct Attach Copper (DAC) cables. This includes SR, LR, and AOC types, ensuring flexible connectivity options for short and long distances.

Modern Data Center Evolution

As applications become more data-intensive, 10GbE networks are increasingly bottlenecked. 25GbE provides 2.5x the bandwidth at comparable cost and power usage, making it an ideal upgrade path for enterprises seeking performance without overhauling infrastructure.

Future-Proof Investment

With backward compatibility to 10GbE and native support for 25GbE, this adapter is ready for next-generation workloads. Its OCP 3.0 form factor also ensures it fits into evolving data center designs and infrastructure.

Competitive Differentiators

Compared to Other Adapters

The P11339-001 stands out with a robust feature set, including extensive offload capabilities, native telemetry, secure firmware, and HPE's enterprise-level support. It competes favorably against Intel XXV710, Broadcom NetXtreme-E, and other Mellanox-based adapters.

Integration with HPE Ecosystem

Unlike third-party NICs, this adapter integrates tightly with HPE tools, diagnostics, and lifecycle management platforms. This ensures smoother deployment, faster troubleshooting, and centralized infrastructure control.

Cost Efficiency and TCO

Despite high-end features, the MCX4621A-ACAB offers a compelling value proposition. Reduced CPU utilization, energy efficiency, and increased VM density translate to a lower total cost of ownership (TCO).

Use in Edge, Hybrid, and Multi-Cloud Environments

Edge Computing

As enterprises move workloads closer to the edge, compact and power-efficient adapters are critical. The MCX4621A-ACAB supports scalable bandwidth in edge environments where latency and connectivity matter most.

Hybrid Cloud Deployments

This adapter bridges on-premises infrastructure with cloud services, offering consistent networking performance across private and public environments. It supports secure tunneling and overlays for hybrid connectivity.

Multi-Cloud Readiness

Organizations leveraging AWS Outposts, Azure Stack, or Google Anthos benefit from the adapter’s cloud-agnostic design. It ensures secure, fast, and manageable connectivity in multi-cloud strategies.

Purchasing and Availability

SKU and Product ID Information

The full part number for this adapter is HPE P11339-001. It may also appear under spare part number MCX4621A-ACAB in some documentation or distributor catalogs.

Channel Availability

This adapter is widely available through authorized HPE distributors, enterprise resellers, and online marketplaces. Ensure authenticity by purchasing from certified partners to maintain warranty coverage and support eligibility.