P43275-B21 HPE Mellanox Ethernet 10/25GB Dual Port SFP28 OCP3 Adapter

Enhanced Product Overview

The HPE P43275-B21 dual‑port network adapter is engineered to deliver dependable high‑bandwidth connectivity for modern data‑center infrastructures. Its OCP 3.0 mezzanine layout, combined with 10GbE/25GbE SFP28 interfaces, provides a versatile foundation for scalable server deployments.

General Specifications

• Manufacturer: HPE
• Part Number: P43275-B21
• Device Type: 2 Ports Network Adapter

Technical Information

• Card Format: Plug‑in mezzanine module
• Bus Interface: OCP 3.0
• PCIe Revision: PCIe 3.0 compliant
• Standards Compliance: Fully aligned with OCP 3.0 guidelines
• Port Configuration: 2 × SFP28 slots
• Supported Ethernet Modes: 10GbE and 25GbE
• Data Link Protocols: 10 Gigabit Ethernet, 25 Gigabit LAN
• Peak Throughput: Up to 25 Gbps

Performance & Network Capabilities

• The adapter is optimized for environments requiring low‑latency packet handling and consistent throughput. Its dual‑speed capability allows flexible deployment across mixed‑bandwidth infrastructures.

Key Advantages

• Reliable high‑speed data transmission for demanding workloads
• Efficient bandwidth utilization across virtualized and clustered systems
• Enhanced compatibility with HPE Gen10 server families

Compatibility

The P43275‑B21 module is designed to integrate seamlessly with a wide range of HPE ProLiant and Nimble Storage DHCI systems.

Supported Server Models

• ProLiant DL110 Gen10
• ProLiant DL325 Gen10 / Gen10 Plus
• ProLiant DL345 Gen10
• ProLiant DL360 Gen10
• ProLiant DL365 Gen10
• ProLiant DL380 Gen10
• ProLiant DL385 Gen10
• HPE XL225n Gen10
• HPE XL290n Gen10
• HPE XL645d Gen10

Deployment Scenarios

• Ideal for Nimble Storage DHCI Medium Solutions, this adapter supports hybrid cloud architectures, virtualization clusters, and high‑density compute nodes.

Use‑Case Highlights

• High‑speed interconnects for storage‑heavy workloads
• Enhanced throughput for virtual machine traffic
• Optimized networking for scalable compute environments

HPE P43275-B21 Dual Port SFP28 OCP3 Adapter

The HPE P43275-B21 Mellanox MCX562A-ACAI Ethernet 10/25GB Dual Port SFP28 OCP3 Adapter is an advanced networking solution designed to deliver high-speed, reliable, and efficient connectivity for modern enterprise servers and data center environments. Built around Mellanox networking technology and engineered for HPE server platforms, this Ethernet adapter provides flexible bandwidth capabilities with support for both 10 Gigabit Ethernet and 25 Gigabit Ethernet connectivity. Its dual-port SFP28 interface design enables organizations to increase network performance, improve application responsiveness, and support demanding workloads that require consistent high-throughput communication.

This adapter belongs to the category of high-performance Ethernet network interface cards designed for next-generation data centers, cloud computing environments, virtualization platforms, and enterprise applications. The HPE P43275-B21 integrates advanced networking features, efficient data transfer capabilities, and a compact OCP 3.0 form factor to provide optimized server connectivity while maintaining excellent scalability and operational efficiency.

High-Speed 10Gb and 25Gb Ethernet Connectivity

The HPE P43275-B21 Mellanox MCX562A-ACAI Ethernet Adapter provides dual-port Ethernet connectivity with support for 10GbE and 25GbE network speeds. This flexibility allows organizations to deploy the adapter in a variety of network environments where different bandwidth requirements exist. By supporting 25 Gigabit Ethernet technology, the adapter delivers significantly improved throughput compared with traditional 10 Gigabit networking solutions, making it suitable for applications that require fast data movement and low communication delays.

The SFP28 ports support high-performance optical and direct attach cabling solutions, enabling efficient connections between servers, switches, and other networking infrastructure components. The ability to operate at multiple Ethernet speeds provides investment protection by allowing enterprises to upgrade network performance without replacing server networking hardware.

Dual Port SFP28 Interface

The dual-port SFP28 architecture of the HPE P43275-B21 enables two independent high-speed network connections through a single adapter. This configuration improves network flexibility by allowing administrators to create redundant connections, separate traffic streams, or increase available bandwidth through advanced networking configurations.

Each SFP28 port supports high-speed Ethernet communication while maintaining compatibility with a wide range of supported transceiver and cable options. This makes the adapter adaptable for different data center layouts, including top-of-rack switching environments, high-density server deployments, and enterprise networking infrastructures.

SFP28 Port Technology for Modern Data Centers

SFP28 technology provides an efficient solution for 10GbE and 25GbE networking by combining high bandwidth capability with a compact connector design. The smaller form factor enables greater port density on switches and adapters, helping data centers optimize rack space and improve overall network efficiency.

The HPE P43275-B21 uses SFP28 connectivity to support reliable, high-speed communication between computing resources and network systems. This makes it well suited for applications such as virtualization, database operations, high-performance computing, storage networking, and cloud-based services.

Mellanox MCX562A-ACAI Networking Architecture

The Mellanox MCX562A-ACAI controller integrated into the HPE P43275-B21 adapter is designed to provide advanced Ethernet performance with intelligent networking capabilities. Mellanox adapters are widely recognized for their ability to handle demanding data center workloads by providing efficient packet processing, optimized data movement, and enhanced network scalability.

The adapter architecture is designed to reduce processing overhead on server CPUs by efficiently managing network traffic directly through dedicated hardware resources. This allows servers to maintain higher application performance while handling intensive communication workloads.

Optimized Server Network Performance

The HPE P43275-B21 Ethernet adapter improves server connectivity by providing a dedicated high-bandwidth communication pathway between the server and network infrastructure. In modern data centers, applications increasingly depend on rapid access to data and low-latency communication. A high-performance adapter such as the Mellanox MCX562A-ACAI helps support these requirements by delivering consistent network performance.

With dual-port functionality and multi-speed Ethernet support, the adapter can efficiently manage increasing network traffic demands. This makes it an effective solution for organizations expanding virtualization environments, deploying cloud applications, or supporting data-intensive workloads.

Efficient Data Transfer Capabilities

The HPE P43275-B21 is designed to improve data transfer efficiency through advanced Ethernet processing technologies. High-speed network adapters reduce bottlenecks between servers and network devices, enabling faster access to applications, storage resources, and distributed computing systems.

The adapter supports enterprise environments where large volumes of information must be transferred quickly and reliably. Applications such as analytics platforms, virtualization clusters, and high-performance computing systems benefit from the increased throughput and improved network responsiveness provided by 25Gb Ethernet connectivity.

Enhanced Workload Support

Modern enterprise workloads require networking solutions capable of handling continuous data exchange. The HPE P43275-B21 supports demanding applications by providing stable and efficient communication between server systems and network infrastructure. Its performance characteristics make it suitable for environments where reliability, speed, and scalability are essential.

OCP 3.0 Form Factor Integration

The HPE P43275-B21 Mellanox MCX562A-ACAI adapter uses the Open Compute Project (OCP) 3.0 form factor, which is designed specifically for modern server platforms. OCP 3.0 adapters provide a standardized and flexible approach to server networking by allowing easy integration and replacement of networking modules.

The OCP 3.0 design helps improve server architecture by positioning network connectivity as a modular component. This allows organizations to select appropriate networking capabilities based on performance requirements while simplifying maintenance and future upgrades.

Space-Efficient Server Networking

The compact OCP 3.0 form factor enables efficient use of server space while delivering high-speed Ethernet functionality. By integrating networking capabilities through an OCP interface, servers can maintain optimized internal layouts while providing advanced connectivity options.

This design approach benefits enterprise data centers where rack density, airflow management, and efficient hardware utilization are important considerations. The adapter provides powerful networking functionality without requiring a traditional PCI Express expansion slot.

Compatibility with HPE Server Platforms

The HPE P43275-B21 is engineered for compatibility with supported HPE servers that utilize the OCP 3.0 networking interface. This allows administrators to integrate the adapter into existing HPE infrastructures while maintaining consistent hardware standards and management practices.

By using a purpose-built HPE networking adapter, organizations can achieve dependable compatibility, streamlined deployment, and optimized performance within their server environments.

Modular Networking Advantages

OCP 3.0 modular networking provides flexibility for future infrastructure changes. Organizations can upgrade networking capabilities independently from other server components, allowing easier adoption of faster Ethernet technologies as business requirements evolve.

Enterprise Data Center Applications

The HPE P43275-B21 Mellanox MCX562A-ACAI Ethernet Adapter is designed for a wide range of enterprise applications that require dependable and high-speed network connectivity. Its combination of dual-port SFP28 interfaces, 10/25Gb Ethernet support, and OCP 3.0 compatibility makes it suitable for modern IT environments.

Virtualization and Cloud Computing Environments

Virtualized infrastructures rely heavily on efficient networking because multiple virtual machines share physical server resources. The HPE P43275-B21 provides the bandwidth and connectivity required to support virtualized workloads while helping maintain smooth communication between virtual machines, servers, and network services.

Cloud computing platforms also benefit from high-speed Ethernet adapters because they require fast data exchange between compute resources, storage systems, and management platforms. The adapter helps improve infrastructure efficiency by supporting higher network throughput and flexible deployment options.

Storage and Data Intensive Workloads

Enterprise storage environments require fast and reliable networking to support applications that depend on rapid data access. The HPE P43275-B21 provides the connectivity performance necessary for storage-related workloads, including data migration, backup operations, and distributed storage systems.

High-speed Ethernet connectivity helps reduce delays during data transfers and improves overall system responsiveness. This makes the adapter suitable for organizations managing large datasets and applications requiring continuous access to shared resources.

High Performance Computing

High-performance computing environments depend on efficient communication between interconnected systems. The HPE P43275-B21 supports these environments by providing high-bandwidth Ethernet connectivity designed for applications that require rapid exchange of large amounts of information.

Advanced Ethernet Features and Reliability

The HPE P43275-B21 Mellanox MCX562A-ACAI adapter incorporates advanced networking capabilities designed to improve efficiency, reliability, and scalability. Its intelligent hardware architecture supports demanding enterprise workloads while maintaining consistent network performance.

Improved Network Scalability

As organizations expand their digital infrastructure, network requirements continue to increase. The HPE P43275-B21 supports scalable Ethernet deployments by providing 10GbE and 25GbE connectivity options through dual SFP28 ports.

This scalability enables businesses to adapt their network infrastructure to changing performance requirements while maintaining compatibility with modern Ethernet standards.

Reliable Enterprise Connectivity

Enterprise environments require networking hardware that can operate continuously with dependable performance. The HPE P43275-B21 is designed for professional data center use, providing stable connectivity for mission-critical applications and essential business operations.

Efficient Infrastructure Management

The adapter simplifies network infrastructure management by providing standardized connectivity through the OCP 3.0 platform. Its modular design and compatibility with HPE server ecosystems help administrators deploy and maintain efficient networking environments.