HPE 730065-B21 800GB MLC SATA-6GBPS Hot-Swap SFF SSD

Supported Server Models

Explore a wide array of enterprise-grade systems that seamlessly integrate with our components. These platforms span across rack-mounted, blade, and tower configurations, ensuring broad adaptability and performance consistency.

Compatibility

Designed for data centers and scalable environments, the following rack servers are fully compatible:

• HP ProLiant DL160 Gen8
• HP ProLiant DL320e Gen8
• HP ProLiant DL360e Gen8
• HP ProLiant DL360p Gen8
• HP ProLiant DL380e Gen8
• HP ProLiant DL380p Gen8
• HP ProLiant DL385p Gen8
• HP ProLiant DL560 Gen8

Legacy Rack Systems

Older generation rack servers still benefit from full integration:

• HP ProLiant DL580 G7
• HP ProLiant DL585 G7

Tower Server Compatibility

Ideal for remote offices and standalone deployments, these tower models are supported:

• HP ProLiant ML310e Gen8
• HP ProLiant ML350e Gen8
• HP ProLiant ML350p Gen8

Blade Infrastructure Support

Optimized for modular computing environments, the following blade servers are validated for compatibility:

• HP BladeSystem BL420c Gen8
• HP BladeSystem BL460c Gen8
• HP BladeSystem BL465c Gen8
• HP BladeSystem BL660c Gen8

Workstation-Class Blade

For high-performance computing within blade enclosures:

• HP BladeSystem WS460c Gen8

Scalable Line (SL) Server Compatibility

Tailored for hyperscale and cloud environments, these SL models are fully supported:

• HP SL230s Gen8
• HP SL250s Gen8

Product Overview of HPE 730065-B21 800GB MLC SSD

The HPE 730065-B21 is an enterprise-grade 800GB solid-state drive designed for HPE ProLiant server platforms. Built as a 2.5-inch small form factor (SFF) drive, the unit uses Multi-Level Cell (MLC) NAND flash memory and connects via a SATA 6Gb/s interface. It is positioned as a mainstream-endurance (ME) / enterprise-mainstream (EM) class SSD intended for mixed-use server workloads where cost-per-GB and reliable consistent performance are both important. The product is commonly offered as an HPE-branded assembly (model number MK0800GCTZB in many listings) and is intended to drop into Gen7-compatible drive trays and hot-plug bays for HPE servers.

Technical Specifications

Form Factor

Physically this drive conforms to the SFF 2.5-inch server drive profile and is packaged to fit hot-swap Gen7 drive trays. Its dimensions and bezel/tray compatibility make it an easy drop-in replacement for existing enterprise SATA bays used in ProLiant servers. This makes it an ideal candidate for mixed arrays where you want to swap HDDs for SSDs without redesigning trays or backplanes.

Interface, Throughput and NAND Type

The 730065-B21 uses a SATA III interface with a maximum synchronous transfer rate of 6Gb/s — the standard “6G” SATA speed that ensures broad compatibility with legacy and newer controllers that implement SATA 3.0. The device utilizes MLC NAND flash targeted at mainstream endurance workloads, balancing cost per gigabyte with sustained write endurance suitable for many server applications.

Performance Expectations (Real-world & Published)

In published product listings and specification sheets the drive is shown to deliver strong mixed workload performance for its class. Example nominal performance figures often cited for the 800GB variant include sequential read throughput in the range of ~450–480 MiB/s and sequential write throughput close to ~450 MiB/s, with random IOPS reported in the tens of thousands (e.g., random reads around 61,000 IOPS and random writes around 35,000 IOPS in certain vendor listings). These numbers position the drive as an effective option for application acceleration, OS boot drives, VM hosts with moderate write intensity, and tier-2 database caches.

Use Cases and Deployment Scenarios

Virtualization Hosts & Boot Volumes

The HPE 730065-B21 is well suited for virtualization host boot volumes and datastore caching in environments where read and steady mixed writes are expected, but extremely high DWPD endurance (write-heavy, constant) is not a requirement. Its balance of capacity (800GB) and mixed-use endurance makes it a cost-effective alternative to higher-endurance, higher-cost SSDs when used as a cache tier or for VMs that do not perform heavy sequential writes continually.

Database Acceleration & Tiered Storage

For databases with frequent read amplification and bursts of random reads, adding HPE 730065-B21 drives to a tiered storage architecture will significantly reduce latency compared to HDD tiers. This SSD is highly effective as a read/write cache or as a mid-tier between high-performance NVMe and high-capacity HDD arrays.

Boot/OS Drives for Blade & Rack Servers

In blade server farms and rack deployments—especially those using Gen7 HPE ProLiant hardware—the hot-swap SFF format and Gen7 drive tray compatibility are key operational advantages. IT teams can standardize on this part for boot and local OS images to reduce start-up time and maintenance windows, and to simplify hot-swap replacement procedures.

Comparisons

Choose between Mainstream Endurance (ME) and Mixed Use (MU)

When a buyer is choosing within the HPE SSD ecosystem, they commonly compare three things: endurance (DWPD or workload rating), price per GB, and performance (IOPS / throughput). Mainstream Endurance models such as the 730065-B21 strike a middle ground—more durable than read-intensive drives but less costly than the highest endurance Mixed-Use or Write-Intensive enterprise drives. For many web servers, VM boot volumes, and general application servers, an ME-rated 800GB SSD provides the best value.