MEM-DR564L-CL01-ER64 Supermicro 64GB DDR5 6400MHz RAM

Supermicro MEM-DR564L-CL01-ER64 64GB RAM

The Supermicro MEM-DR564L-CL01-ER64 offers powerful performance with 64GB DDR5 6400MHz Registered DIMM, designed for enterprise servers and intensive workloads.

Manufacturer Information

• Manufacturer: Supermicro
• Model Number: MEM-DR564L-CL01-ER64
• Product Type: 64GB DDR5 SDRAM Module

Technical Specifications

Memory Capacity & Architecture

• Size: 64GB – Ideal for virtualization and heavy-duty computing
• Technology: DDR5 SDRAM – Advanced design with higher bandwidth
• Configuration: 1 x 64GB – Single DIMM for scalable setups

Performance Features

• Speed: 6400MHz – Ultra-fast for demanding applications
• Standard: DDR5-6400 / PC5-51200 – Next-gen enterprise memory
• Signal: Registered – Ensures stability and integrity
• Rank: Dual Rank – Boosts throughput and supports larger capacity
• Error Correction: ECC – Reliable error handling to minimize downtime
• Latency: CL52 – Low latency for faster processing

Compatibility & Efficiency

• Pin Count: 288-pin – Standard RDIMM for modern boards
• Voltage: 1.1V – Energy-efficient design
• Form Factor: RDIMM – Enterprise-ready memory format

Physical Characteristics

Dimensions

• Size (W x D x H): 5.2 x 1.2 x 0.2 in – Slim profile for easy installation

Weight

Lightweight Design

• Shipping Weight: 0.20 lb – Easy to handle and transport

Supermicro MEM-DR564L-CL01-ER64 64GB DDR5 RAM Overview

The Supermicro MEM-DR564L-CL01-ER64 64GB DDR5 6400MHz server memory module belongs to the advanced enterprise DDR5 ECC Registered DIMM category designed for modern data center infrastructures. This category focuses on delivering high bandwidth, superior reliability, enhanced power efficiency, and scalable memory capacity for mission-critical server workloads. As server processors continue to increase core counts and memory channel density, DDR5 RDIMM solutions have become essential components for maximizing overall system throughput and stability.

DDR5 server memory represents a generational leap from DDR4 technology by introducing higher data transfer rates, improved signal integrity, on-module power management, and increased bank groups. The MEM-DR564L-CL01-ER64 module exemplifies this evolution by offering PC5-51200 performance at 6400MHz, enabling faster data access for compute-intensive applications such as virtualization, artificial intelligence processing, in-memory databases, and large-scale analytics environments.

DDR5 RDIMM Architecture and Design Characteristics

Registered Dual In-Line Memory Modules are engineered to support large memory capacities and multi-DIMM configurations within server platforms. The registered design incorporates a register chip that buffers command and address signals, significantly improving signal quality and system stability when operating at high frequencies. This architecture allows servers to populate more memory modules per channel without sacrificing reliability or performance consistency.

The MEM-DR564L-CL01-ER64 module utilizes a 2Rx4 configuration, which indicates two memory ranks with x4 DRAM chips. This structure enhances memory interleaving and parallelism, enabling more efficient data handling under heavy workloads. The 288-pin form factor ensures compatibility with DDR5-enabled server motherboards, particularly those designed for next-generation Intel Xeon and AMD EPYC platforms.

ECC Registered Memory for Data Integrity

Error Correcting Code functionality is a defining feature of enterprise server memory categories. ECC technology detects and corrects single-bit memory errors in real time, preventing data corruption and reducing the risk of system crashes. In environments where uptime, data accuracy, and transactional integrity are critical, ECC Registered memory modules such as the Supermicro MEM-DR564L-CL01-ER64 provide essential safeguards.

This category is especially valuable in applications involving financial transactions, scientific simulations, healthcare databases, and virtualization clusters where even minor memory errors can lead to costly downtime or inaccurate results. The ECC capability operates transparently, ensuring that system performance remains uncompromised while maintaining high reliability.

High-Frequency 6400MHz Performance Class

Operating at 6400MHz, this DDR5 server memory module sits within the high-performance tier of the PC5-51200 classification. This frequency delivers substantial improvements in bandwidth compared to previous DDR4 generations, allowing processors to access data more rapidly and efficiently. Higher memory bandwidth is particularly beneficial for workloads that rely on fast memory access, including real-time analytics, cloud computing services, and high-performance computing clusters.

The CL52 latency rating is optimized for DDR5 operating characteristics, balancing speed and stability at elevated data rates. While raw latency numbers differ from DDR4 due to architectural changes, the overall effective performance of DDR5 at 6400MHz provides a measurable uplift in real-world server workloads.

Power Efficiency and Voltage Optimization

One of the major advancements in the DDR5 server memory category is improved power efficiency. The Supermicro MEM-DR564L-CL01-ER64 operates at a reduced voltage of 1.1V, which lowers overall power consumption compared to previous memory generations. This efficiency gain contributes to reduced thermal output, improved energy management, and lower operational costs in large-scale data center deployments.

DDR5 modules integrate on-module power management integrated circuits, shifting voltage regulation from the motherboard to the memory module itself. This design enhances power delivery accuracy and stability, particularly under fluctuating workloads. As a result, servers can maintain consistent performance while optimizing power usage across memory-intensive tasks.

Thermal Stability in Dense Server Configurations

High-capacity memory modules operating at elevated frequencies generate heat that must be managed effectively. The DDR5 RDIMM category emphasizes thermal stability through improved PCB layouts, optimized component placement, and efficient power regulation. These enhancements ensure reliable operation in densely populated server chassis where airflow may be constrained.

Maintaining thermal stability is essential for sustaining peak performance over extended periods. The MEM-DR564L-CL01-ER64 module is designed to operate within enterprise thermal specifications, supporting continuous workloads without throttling or performance degradation.

Scalability for Modern Server Platforms

Scalability is a defining requirement of enterprise memory categories. The 64GB capacity of this DDR5 RDIMM module enables servers to scale memory resources efficiently to meet growing application demands. When deployed across multiple channels and DIMM slots, this category supports multi-terabyte memory configurations suitable for virtualization hosts, enterprise databases, and software-defined infrastructure.

Modern server CPUs leverage multiple memory channels to maximize throughput. DDR5 RDIMM modules are engineered to fully utilize these channels, ensuring balanced memory access and optimal performance scaling as additional modules are installed.

Compatibility with Supermicro Server Ecosystems

As a Supermicro-branded memory solution, the MEM-DR564L-CL01-ER64 is validated for compatibility with Supermicro server and motherboard platforms. This validation process ensures proper firmware recognition, stable operation, and optimal performance when integrated into supported systems.

Enterprise buyers benefit from reduced deployment risks and simplified system qualification when using vendor-approved memory modules. Compatibility assurance is especially important in production environments where system stability and vendor support are critical considerations.

Use Cases Across Enterprise and Cloud Workloads

The DDR5 ECC Registered memory category addresses a wide range of enterprise and cloud computing use cases. Virtualization environments benefit from increased memory bandwidth and capacity, enabling higher virtual machine density and improved performance isolation. In-memory databases leverage fast DDR5 access speeds to accelerate query execution and transactional processing.

Artificial intelligence and machine learning workloads rely heavily on memory throughput to feed data to accelerators and CPUs. High-frequency DDR5 RDIMM modules support faster data preprocessing and model training, reducing overall computation time. Similarly, content delivery networks, web hosting platforms, and containerized applications gain performance advantages from improved memory responsiveness.

High-Performance Computing and Scientific Applications

High-performance computing environments demand consistent, low-latency access to large datasets. The MEM-DR564L-CL01-ER64 module fits seamlessly into this category by providing the bandwidth and reliability required for simulations, modeling, and data analysis tasks. ECC protection ensures computational accuracy, which is essential in research and engineering applications.

Scientific workloads often operate continuously for extended durations, making memory stability and thermal efficiency critical factors. DDR5 RDIMM solutions are designed to meet these demands while delivering scalable performance.

Signal Integrity and Advanced Memory Topology

DDR5 memory introduces enhanced signaling techniques to support higher frequencies and improved data integrity. The registered architecture of RDIMM modules further strengthens signal quality by reducing electrical load on the memory controller. This combination enables stable operation at 6400MHz even in multi-DIMM configurations.

Improved bank group architecture in DDR5 increases parallelism and reduces access contention. This architectural refinement allows servers to handle concurrent memory requests more efficiently, which is particularly advantageous in multi-threaded and multi-user environments.

Latency Optimization within DDR5 Standards

While DDR5 introduces higher nominal latency values compared to DDR4, the overall system-level latency is mitigated by increased bandwidth and architectural efficiencies. The CL52 timing of this module is aligned with JEDEC DDR5 specifications, ensuring predictable performance across supported platforms.

For enterprise workloads, consistent and reliable latency is often more important than minimal raw latency. DDR5 RDIMM modules deliver this consistency, supporting predictable application behavior and improved quality of service.