P12392-B21 HPE Proliant E910 4Ports 10GBE QSFP+ Module.

P12392-B21 HPE ProLiant E910 4Ports 10GBE QSFP+ Expansion Module Overview

The P12392-B21 HPE ProLiant E910 4Ports 10GBE QSFP+ Expansion Module is a high-performance network interface expansion card designed specifically for the HPE ProLiant E910 server platform. Delivering enterprise-grade 10 Gigabit Ethernet connectivity via QSFP+ ports, this expansion module is engineered for modern data centers requiring robust, low-latency, and scalable networking performance. Whether deployed in a hyper-converged infrastructure, virtualized environment, or high-bandwidth application, this module ensures seamless and reliable data throughput for mission-critical operations.

Designed for HPE ProLiant E910 Modular Servers

This 4-port 10GbE QSFP+ expansion module is purpose-built for the HPE ProLiant E910 server chassis. As part of the HPE Synergy and Composable Infrastructure ecosystem, the E910 server is a modular blade solution optimized for agility and scale. The P12392-B21 module expands networking capabilities within the E910 platform, offering flexibility to scale bandwidth and reduce bottlenecks. It integrates natively with HPE’s management tools, such as HPE OneView, simplifying network provisioning and monitoring across complex IT environments.

Seamless Integration and Compatibility

Engineered to match the physical and logical infrastructure of the HPE ProLiant E910 server, the P12392-B21 module ensures a plug-and-play experience. It fits within designated mezzanine or expansion slots without requiring additional cables or adapters. The module also supports PCIe Gen3 bus architecture and integrates with HPE's server management stack, providing BIOS-level visibility and remote manageability for consistent operational control.

Performance and Networking Capabilities

The P12392-B21 4-port 10GbE QSFP+ Expansion Module brings significant improvements in data throughput and low-latency communication. Designed to meet the high-demand networking needs of virtualization, big data, and cloud workloads, the module empowers enterprises to keep pace with rapid data growth and evolving application demands.

High-Bandwidth 10GbE QSFP+ Ports

This module features four 10 Gigabit Ethernet QSFP+ ports, enabling simultaneous high-speed connections to network fabrics, switches, or other servers. Each QSFP+ port supports multiple lane configurations, allowing compatibility with breakout cables and adaptation to different link topologies. These ports are ideal for use in leaf-spine data center architectures or for direct server-to-server connections in HPC or cluster environments.

Flexible Topology

The QSFP+ interfaces can be configured for different network designs, such as single-mode or multi-mode fiber, DAC (Direct Attach Copper) cabling, or even split-out configurations for 4x10GbE breakout from 40GbE uplinks, providing unmatched versatility for network engineers and architects.

Low Latency and High Packet Processing

Engineered with hardware offloading and intelligent packet routing capabilities, the P12392-B21 reduces CPU overhead by handling tasks such as checksum offload, TCP segmentation offload (TSO), and large receive offload (LRO). This frees up compute resources for other critical workloads, increasing overall system performance and efficiency.

Advanced Features for Virtualization

Virtualization support is integral to modern data center solutions, and the P12392-B21 delivers with technologies like SR-IOV (Single Root I/O Virtualization) and VLAN tagging. SR-IOV enables direct assignment of network resources to virtual machines, reducing latency and increasing throughput, particularly in virtualized environments running hypervisors such as VMware ESXi, Microsoft Hyper-V, and KVM.

Reliability, Security, and Manageability

Beyond raw performance, the P12392-B21 HPE ProLiant expansion module offers enterprise-class reliability, embedded security features, and remote manageability to support 24/7 operations in mission-critical environments. HPE integrates multiple layers of protection and control into its networking modules to help ensure infrastructure resilience and business continuity.

Redundant Networking Options

With four independently functioning 10GbE ports, the module supports redundancy and load balancing configurations. Using NIC teaming or bonding, IT administrators can ensure network failover capability and maximize throughput under heavy loads.

Firmware Resilience and Secure Boot

Firmware-level integrity checking helps protect against unauthorized code execution. HPE’s secure boot technology verifies the authenticity and integrity of the firmware and boot environment, ensuring that only validated code is loaded on system start-up.

Advanced Diagnostics and Remote Management

Built-in diagnostic tools support real-time traffic monitoring, error reporting, and configuration rollback. When used with HPE iLO (Integrated Lights-Out) and HPE OneView, the module allows remote firmware upgrades, configuration tuning, and health monitoring, reducing the need for on-site intervention.

Environmental Efficiency

Designed to meet HPE’s Green IT initiatives, the module operates within a wide thermal range while maintaining energy efficiency. Smart power-down features and adaptive load balancing help reduce power consumption without compromising performance, aligning with sustainability goals in modern data centers.

Use Cases for the P12392-B21 HPE ProLiant E910 4Ports 10GBE QSFP+ Expansion Module

This module caters to a broad array of applications across industries, thanks to its powerful 10GbE connectivity and modular form factor. Below are some of the most common deployment scenarios:

High-Performance Computing (HPC)

In scientific computing, engineering simulations, and AI workloads, the need for high-speed inter-node communication is critical. The P12392-B21’s 10GbE QSFP+ interfaces provide the low-latency, high-throughput links required for fast cluster communication and data aggregation.

Virtualization and Cloud Infrastructure

Cloud service providers and enterprises hosting virtualized workloads benefit from the module’s SR-IOV, VLAN tagging, and QoS support. These features allow precise traffic control and optimal VM networking, reducing jitter and improving application responsiveness.

Big Data Analytics

In environments processing petabytes of data—such as data lakes and Hadoop clusters—the high throughput offered by this module ensures rapid data movement between nodes and storage arrays, enabling faster insights and analytics cycles.

Media and Content Delivery

For streaming services, video rendering, and digital content delivery networks (CDNs), 10GbE networking enables low-buffer latency and fast file transfers, improving end-user experience and operational scalability.

Driver and Firmware

HPE provides updated drivers and firmware packages for the P12392-B21 through its official support portal. These updates ensure compatibility with the latest operating systems, performance tuning, and security patches. Firmware management can be handled manually or automated via HPE Smart Update Manager (SUM) and HPE OneView integrations.

Advantages of Choosing the HPE P12392-B21 Module

For businesses relying on HPE’s server ecosystems, the P12392-B21 represents a critical building block in achieving high-throughput, resilient, and scalable networking infrastructure. Here are a few of the major benefits:

Optimized for HPE Ecosystem

Designed in-house by HPE, this module is guaranteed to perform within specified tolerances in the E910 chassis. It is tested across firmware updates and OS changes, offering peace of mind with long-term support and compatibility.

Future-Proofed Networking

10GbE remains the de facto standard for enterprise workloads, and the flexibility of QSFP+ allows upgrade paths to 40GbE or 100GbE. Businesses can adopt the P12392-B21 now and continue scaling without rip-and-replace costs.

Reduced TCO

By enabling virtualization offload, lowering CPU utilization, and reducing cabling complexity, this expansion module supports IT cost optimization initiatives. When integrated with software-defined networking (SDN) platforms, it also reduces manual intervention and provisioning time.

High Availability Architecture

Redundant port design, robust driver support, and firmware stability make this module ideal for 99.999% uptime environments where availability and reliability are non-negotiable.

Ordering and Deployment Considerations

IT managers considering deployment of the P12392-B21 should evaluate their server rack density, existing cabling infrastructure, and workload types. The module pairs best with HPE-supported QSFP+ transceivers and cables, and HPE provides a matrix of tested components to ensure interoperability. Procurement through authorized HPE resellers ensures genuine parts and warranty compliance.