P43263-001 HPE 16GB DDR5 4800MHz PC5-38400 1Rx8 ECC 288-pin Rdimm Smart Memory Module

HPE P43263-00116GB DDR5 4800MHz PC5-38400 RDIMM

The P43263-001 HPE 16GB DDR5 4800MHz PC5-38400 1Rx8 ECC 288-pin RDIMM Smart Memory Module is engineered for modern HPE ProLiant and enterprise server platforms that demand a balance of capacity, reliability, and performance. This module represents a standard building block for memory expansion in data centers, virtualization hosts, database servers, and high-performance computing nodes where stable, error-correcting memory is required.

Reliability and ECC

ECC (Error-Correcting Code) makes the P43263-001 suitable for mission-critical workloads. ECC corrects single-bit errors and detects multi-bit errors, improving uptime for database systems, virtualization clusters, and memory-intensive applications. In enterprise environments, ECC memory is a foundational element of resilient system design.

Technical deep-dive DDR5 advantages and RDIMM characteristics

DDR5 architecture brings important improvements over DDR4, including higher bandwidth per module, improved channel architecture, on-die ECC, and better power efficiency at scale. The P43263-001 leverages DDR5’s 4800MT/s speed grade (PC5-38400), often delivering measurable throughput improvements for memory-bound workloads.

RDIMM versus UDIMM and LRDIMM

Registered DIMMs (RDIMMs) include a register between the DRAM modules and the memory controller. That register buffers control signals and improves signal integrity when many DIMMs are populated—making RDIMM the preferred choice for server systems where high-density memory configurations are common.

Compatibility and platform fit

The P43263-001 is specifically qualified by HPE to work with targeted HPE server families. Using HPE-branded Smart Memory reduces the risk of compatibility errors and ensures the system BIOS/firmware recognizes the module and applies optimal settings automatically. Always consult the HPE server memory compatibility matrix or the server Quick Specs before purchasing large quantities.

Common compatible HPE platforms

Typical compatible platforms include various HPE ProLiant Gen10/Gen11 servers and select HPE Apollo or HPE Synergy systems that support DDR5 RDIMM. Actual compatibility depends on the server model and firmware revision — verify using HPE support resources or the server’s memory population guide.

Cross-reference and alternate part numbers

Enterprises often track HPE spare part numbers and cross-references. The P43263-001 may have alternate ordering numbers for service spares or be listed in bundles with other memory configurations. When replacing memory, match the exact MPN where possible for guaranteed SEP support and Smart Memory benefits.

Performance characteristics and expected real-world impact

At 4800MT/s, a PC5-38400 module provides solid bandwidth for multi-threaded applications, in-memory databases, and virtualization hosts. The actual performance gain versus lower-speed modules will vary by workload—memory-latency-sensitive workloads benefit from faster clock rates, while capacity-bound workloads benefit primarily from added gigabytes.

Memory bandwidth vs latency

DDR5 increases peak bandwidth, but application performance also depends on latency and memory controller efficiency. For many enterprise applications (e.g., large databases, caching layers, analytics), aggregate bandwidth improvements from DDR5 can reduce query latencies and improve throughput when paired with adequate CPU and I/O subsystems.

Population rules and channel balancing

Always populate DIMMs across memory channels to maximize interleaving. For example, with a dual-socket system, ensure each CPU’s memory channels are balanced to avoid asymmetric performance. When combining modules of different capacities or speed grades, the system may downclock modules to the slowest common speed or apply mixed-mode timings—this is why matching modules (same part number and speed) is recommended.

Mixing memory modules what to know

Mixing RDIMMs with different capacities, ranks, or manufacturers can cause the system to default to the most conservative timing and voltage settings, potentially reducing performance. Some platforms tolerate mixed configurations but may disable certain features. For production environments, use identical P43263-001 modules for predictable results and to preserve Smart Memory benefits.

Rank and organization considerations

The P43263-001 is 1Rx8 (single-rank, x8). When mixing ranks (e.g., single-rank with dual-rank), the memory controller’s behavior will vary. Some servers prefer matched ranks across channels for optimal interleaving. Refer to the server’s memory guidelines for recommended rank mixes.

Common diagnostic indicators

Look for ECC correction events, uncorrectable ECC errors, or POST codes indicating SPD or memory initialization failures. Correctable errors can be normal but should be tracked—an increasing trend may indicate failing DIMMs or a marginal electrical environment (e.g., shock, thermal stress). Uncorrectable errors often require immediate DIMM replacement.

Thermal and power considerations

DDR5 modules operate with integrated power management improvements, but high-density RDIMM configurations increase system power draw and heat. HPE systems are designed with appropriate airflow and thermal management, but be mindful of rack airflow patterns and ambient temperatures when populating many modules.

Purchasing guidance and procurement tips

When buying P43263-001 modules, consider vendor warranty, return policies, and whether modules are new or refurbished. HPE-branded Smart Memory often includes HPE support pathways that generic or third-party modules might not provide. For large-scale procurements, request HPE compatibility confirmation or purchase through authorized HPE channels to ensure service coverage.

Cost versus value considerations

While HPE-branded modules may cost more than commodity memory, their compatibility assurance, warranty, and Smart Memory features provide value in enterprise deployments where downtime and incompatibility are costly. Weigh initial acquisition costs against long-term support and reduced troubleshooting.

Use cases and ideal workloads

The P43263-001 16GB DDR5 RDIMM is ideal across a variety of enterprise and SMB scenarios:

Virtualization and cloud hosts

Populate hosts with multiple 16GB modules to scale VM density while retaining ECC protection. The 4800MT/s speed helps with memory-intensive guest workloads and faster snapshot/clone operations in hypervisor environments.

Database servers and analytics

Databases that store working sets in memory will benefit from DDR5 bandwidth increases. ECC ensures data integrity when performing large in-memory operations or analytics queries.

Application servers and mid-tier systems

Web servers, application stacks, and middleware often require predictable memory performance and stability—attributes delivered by Smart Memory RDIMMs like P43263-001.

P43263-001 vs alternative memory options

Choosing between different memory part numbers and types requires evaluating capacity, speed, rank, and manufacturer support. The P43263-001 strikes a middle ground with 16GB capacity and 4800MT/s speed; alternatives might trade capacity for speed (e.g., 32GB on a different part number) or choose LRDIMM for larger capacities per module.

When to choose larger capacity modules

If total system memory requirements exceed what 16GB modules can efficiently provide without consuming all DIMM slots, consider 32GB or 64GB modules. However, larger modules can be more expensive per module and may alter memory population strategies.

When smaller modules may be preferable

In distributed environments where spare parts must be economical and flexible, 16GB modules provide a balance between cost and scalability. They allow more granular increments of capacity during upgrades.

Optimizing meta-descriptions and product snippets

A concise, benefit-focused snippet helps click-through rates. Example short snippet: "HPE P43263-001 16GB DDR5 RDIMM — 4800MT/s PC5-38400, ECC, Smart Memory for HPE ProLiant servers. Reliable, HPE-qualified memory module for production deployments."

HPE memory modules comply with international regulatory standards for electronic components. Check product documentation for specifics about RoHS, WEEE, and other regional compliance requirements.

End-of-life and recycling

Follow local regulations for e-waste disposal and recycling. Many vendors offer recycling programs for retired server components.

Additional recommendations for large deployments

For enterprise rollouts, perform a pilot deployment to validate firmware compatibility and observe performance and error logging. Maintain a spare parts inventory of P43263-001 modules to facilitate rapid replacement in the field, and coordinate firmware baselines across systems to minimize incompatibility.