P69728-B21 HPE 64GB DDR5-6400MHz PC5-51200 Memory

P69728-B21 HPE 64GB DDR5 Smart Memory Kit: Enterprise-Grade Performance

The P69728-B21 HPE 64GB (1x64GB) Dual Rank x4 DDR5-6400MHz Smart Memory Kit stands at the forefront of next-generation server memory. Engineered for HPE ProLiant servers, this DDR5 Registered DIMM (RDIMM) combines blazing speeds, enhanced bandwidth, and enterprise-level reliability to meet the needs of modern data centers, virtualization workloads, and mission-critical applications. Operating at a frequency of 6400 MHz and built using high-density DRAM technology, it represents a critical leap forward in server memory evolution.

DDR5 RDIMM Technology: Redefining Server Memory Standards

DDR5 memory brings sweeping improvements over DDR4, including increased bandwidth, improved power efficiency, and superior signal integrity. The P69728-B21 module capitalizes on these features to deliver improved scalability and system performance across compute-intensive environments.

Bandwidth and Frequency Enhancements

With a data transfer rate of 6400 MT/s (PC5-51200), this module facilitates faster data access and improved throughput, essential for database processing, virtualization, high-performance computing (HPC), and large-scale enterprise applications. The high-speed interface ensures a lower latency profile even under concurrent, high-demand operations.

Power Efficiency with 1.1V Operation

DDR5 memory modules such as this HPE 64GB kit operate at a lower voltage (1.1V) compared to DDR4’s 1.2V, offering improved energy efficiency without compromising performance. This not only reduces thermal output but also lowers overall data center operating costs.

Registered ECC Memory for Server-Grade Reliability

The P69728-B21 Smart Memory Kit features ECC (Error-Correcting Code) with 8-bit DRAM-based correction (EC8), which plays a critical role in minimizing data corruption and maintaining operational consistency. As a Registered DIMM, it also supports buffering to offload the memory controller, enabling higher densities and better scalability.

ECC Capabilities: Protecting Data Integrity

By continuously monitoring and correcting single-bit memory errors, ECC ensures a more stable computing environment—especially vital in financial modeling, AI inference, real-time analytics, and other workloads that demand precision.

Smart Memory Certification

HPE Smart Memory undergoes extensive validation and is engineered to seamlessly integrate with HPE servers and management software like HPE iLO. This guarantees compatibility, performance consistency, and access to advanced memory diagnostics that standard off-the-shelf memory kits simply don’t provide.

Dual Rank x4 Configuration: Balanced Throughput and Density

The dual-rank x4 DRAM architecture of this module optimizes system balance between memory access speed and capacity scaling. This configuration promotes higher performance per DIMM and is ideal for applications with mixed read/write loads such as virtualized infrastructure, container orchestration, and software-defined storage environments.

Increased RAS (Reliability, Availability, Serviceability)

The x4 DRAM width and dual-rank setup contribute to advanced memory fault tolerance mechanisms. These include features like command/address parity and write CRC that ensure reliable memory operations even under high stress.

288-Pin DIMM Form Factor

This module complies with the JEDEC DDR5 DIMM standard and uses a 288-pin layout. This ensures backward-compatible physical installation in HPE Gen11 and Gen10 Plus platforms while also leveraging higher electrical performance and cleaner signaling.

Ideal Platforms and Compatibility

• Optimized for HPE ProLiant DL and ML Gen11 Servers
• Backward compatible with HPE Gen10 Plus platforms supporting DDR5
• Compatible with HPE Smart Array and Smart Memory diagnostics utilities

Security and Management with HPE Smart Features

One of the standout features of the HPE Smart Memory portfolio is its firmware integration with server BIOS and iLO. This enables real-time memory health monitoring, failure prediction, and improved power budgeting—features critical for large-scale environments and enterprises that prioritize uptime and predictive maintenance.

Memory Authentication and Integrity Checks

The module supports real-time authentication checks via HPE firmware, preventing counterfeit or incompatible DIMMs from impacting server operations. Each DIMM’s unique identifier and firmware profile allow detailed analytics and lifecycle reporting through tools like HPE InfoSight.

Scalability for Future-Ready IT Infrastructure

As the server industry transitions toward DDR5 platforms, the P69728-B21 64GB Smart Memory Kit provides a flexible, scalable memory foundation for hybrid cloud, AI/ML, and containerized application workloads. With support for larger memory footprints and higher parallelism, it helps enterprises stay ahead of escalating memory demands.

Support for High-Density Memory Configurations

Data centers running virtualization stacks, VDI environments, or large databases benefit from higher capacity modules like this 64GB RDIMM. Combined with other DDR5 modules, it can help scale server memory up to terabytes without bottlenecking bandwidth or compute resources.

Real-World Workloads that Benefit

• Artificial Intelligence (AI) and Machine Learning (ML)
• Virtualization and Hyper-Converged Infrastructure (HCI)
• Cloud-native microservices and orchestration layers
• Database and in-memory analytics
• Content delivery and caching systems

Comparison with Legacy DDR4 Memory Kits

Compared to the previous generation DDR4 memory, the HPE P69728-B21 DDR5 kit delivers more than 50% bandwidth improvement, a significant reduction in latency, and up to 30% power efficiency gains. The leap to DDR5 also enables per-channel voltage regulators and higher DIMM densities, marking a shift in how server memory is designed and managed.

Bandwidth and Speed Advantages

Whereas DDR4 modules peak around 3200 MT/s, the P69728-B21 DDR5 operates at 6400 MT/s, doubling the data transfer capabilities. This enhancement directly translates to quicker access to datasets and better performance in multi-threaded, memory-intensive applications.

Operational Power Efficiency

DDR5's power-efficient architecture—combined with the module’s 1.1V spec—means lower energy consumption across thousands of DIMMs in a large-scale deployment. That, in turn, enables cooler operations and reduced dependency on aggressive cooling infrastructure.

Advanced Thermal Management

The P69728-B21 is designed with thermally optimized PCB layout and onboard sensors that integrate with HPE system firmware to enable real-time thermal throttling and diagnostics. This thermal telemetry is vital for high-density racks where thermal margins are tight and memory hotspots can create performance degradation risks.

Heat Spreaders and PCB Optimization

Integrated heat spreaders and multilayer PCB design ensure that heat is dissipated evenly across the module, enhancing overall thermal performance. This makes it ideal for high-density server deployments where airflow and thermal zones are tightly regulated.

Choose HPE Certified Smart Memory

Unlike third-party memory modules, HPE Smart Memory such as the P69728-B21 is validated through over 3 million hours of testing across a range of server and workload scenarios. This depth of qualification ensures predictable behavior, enhanced BIOS-level tuning, and future firmware compatibility.

Full Integration with HPE Software Stack

By choosing Smart Memory, customers unlock support for advanced management features within HPE OneView, HPE iLO, and HPE Insight Diagnostics. These tools allow remote diagnostics, lifecycle tracking, and predictive alerts based on real-world telemetry.