Supermicro MEM-DR525PE-ER64 256GB Pc5-51200 DDR5 6400MHz ECC RDIMM Memory

Highlights of Supermicro MEM-DR525PE-ER64 256GB DDR5 Ram

The Supermicro MEM-DR525PE-ER64 is a high-capacity DDR5 RDIMM memory module designed for enterprise servers and data centers. With a speed of 6400MHz, quad-rank architecture, ECC support, and low voltage operation, this 256GB memory module ensures top-tier performance, stability, and reliability for mission-critical workloads.

General Information

• Manufacturer: Supermicro
• Part Number: MEM-DR525PE-ER64
• Product Type: Server Memory Module
• Sub Type: DDR5 6400MHz SDRAM PC5-51200

Technical Specifications

• Memory Size: 256GB
• Memory Rank: Quad Rank (4Rx4)
• Bus Speed: DDR5-6400 / PC5-51200
• CAS Latency: CL52
• Voltage: 1.1V
• ECC Support: Error-Correcting Code
• Registered DIMM: RDIMM architecture for stability
• High-Density Module: Component composition

Physical Characteristics

Form Factor & Dimensions

• Form Factor: 288-Pin RDIMM
• Number of Pins: 288

Compatibility

Supported Servers & CPU Platforms

• Supermicro X13 series and newer servers designed for DDR5 memory
• Servers powered by 4th Gen Intel® Xeon® Scalable processors (Sapphire Rapids)
• Compatible with AMD EPYC™ 9004 series (Genoa) platforms supporting DDR5-6400 RDIMM modules

Memory Slot & Form Factor Requirements

• Requires standard 288-pin RDIMM sockets on supported server motherboards
• Only supports ECC Registered DDR5 memory; incompatible with non-ECC or desktop UDIMM slots

BIOS & Firmware Considerations

• Ensure the server BIOS/firmware is updated to recognize DDR5-6400 RDIMM modules
• Some server platforms may require specific BIOS configurations for proper memory operation

Overview of Supermicro MEM-DR525PE-ER64 DDR5 6400MHz

The Supermicro MEM-DR525PE-ER64 256GB DDR5 6400MHz PC5-51200 RDIMM 4Rx4 ECC Registered Cl52 1.1v 288-Pin memory module represents a top-tier category of enterprise-grade server memory engineered to support high-performance, mission-critical applications in modern data centers. This category of memory modules delivers extreme capacity, ultra-high bandwidth, and advanced error-correcting reliability, making it suitable for next-generation server deployments that require massive memory throughput, low latency, and scalable performance across multi-socket systems. The MEM-DR525PE-ER64 modules are designed to meet the needs of enterprises seeking to deploy large-scale virtualization clusters, in-memory databases and high-performance computing (HPC) applications while maintaining full ECC reliability and energy-efficient operation.

DDR5 6400MHz Performance and Bandwidth

Operating at 6400MHz, the MEM-DR525PE-ER64 modules provide exceptional performance and unmatched bandwidth for enterprise servers. The PC5-51200 specification allows for rapid data transfers between the CPU and memory, reducing latency and improving throughput for workloads that demand high-speed memory access. Applications such as virtualization, cloud computing, real-time analytics, large-scale databases, and AI training models benefit significantly from the higher data rates of DDR5 memory. High-frequency memory access ensures that multiple cores can process large volumes of data concurrently without bottlenecks, providing consistent and predictable server performance.

256GB Capacity for Extreme Memory-Intensive Workloads

The 256GB capacity per module positions the MEM-DR525PE-ER64 category for use in memory-intensive enterprise applications and high-performance servers. With this capacity, data centers can deploy servers capable of hosting massive virtualized environments, large in-memory databases, complex analytics platforms, and high-throughput cloud applications. The large module size reduces the number of DIMMs required to reach high memory capacities, simplifying server design while minimizing memory channel congestion and maximizing signal integrity. This category is particularly suited for high-density server clusters deployments, HPC simulations, and mission-critical enterprise workloads where large memory pools are required to store and process vast datasets.

RDIMM Architecture and System Stability

The MEM-DR525PE-ER64 memory modules use Registered DIMM (RDIMM) architecture to enhance system stability and signal integrity in high-density and multi-socket server configurations. The register buffers electrical signals between the memory controller and DRAM chips, allowing servers to support more DIMMs per channel without risking signal degradation or performance instability. RDIMM modules are ideal for enterprise servers that operate continuously under high workloads and require robust memory reliability. This architecture ensures that servers can maintain stable operation across multiple memory channels, even when fully populated with high-capacity modules.

4Rx4 Quad-Rank Memory Organization

The MEM-DR525PE-ER64 modules employ a 4Rx4 quad-rank configuration, distributing memory across four ranks of x4 DRAM chips. Quad-rank modules allow for higher memory capacities per DIMM while maintaining optimal memory channel efficiency. This organization enables IT administrators to maximize memory population in multi-socket servers without introducing excessive electrical load or signal degradation. The 4Rx4 configuration is particularly effective in large-scale enterprise deployments, HPC clusters, and data centers that require massive memory pools for virtualization, analytics, or scientific computation.

288-Pin DDR5 Form Factor

The MEM-DR525PE-ER64 modules adhere to the 288-pin DDR5 RDIMM standard, ensuring compatibility with modern enterprise server motherboards designed for DDR5 memory. This standardization supports high-speed signaling, stable voltage delivery, and efficient thermal dissipation, which are critical for maintaining performance in servers populated with multiple high-capacity modules. IT administrators can confidently deploy these modules across supported platforms, knowing that the 288-pin form factor ensures interoperability and predictable system behavior. Standardized form factor modules simplify memory upgrades, replacements, and scaling across multi-node clusters, reducing operational complexity and supporting enterprise deployment best practices.

Supermicro Servers

The MEM-DR525PE-ER64 category is optimized and validated for Supermicro enterprise server platforms, ensuring full compatibility with recommended voltage, timing, and thermal specifications. Validation testing provides enterprise IT teams with confidence that servers populated with these modules will perform reliably under sustained workloads. While these modules are designed for Supermicro servers, they are generally compatible with other DDR5-compliant platforms, although system-level verification is recommended for maximum performance and stability.

Scalability for Large Enterprise Workloads

The MEM-DR525PE-ER64 memory modules provide exceptional scalability for enterprise servers, HPC clusters, and cloud infrastructure. Multiple 256GB modules can be deployed across server DIMM slots to achieve total memory capacities of several terabytes per system. This scalability allows IT administrators to efficiently provision memory for virtualized workloads, large in-memory databases, real-time analytics, AI model training, and high-performance computing applications. The combination of RDIMM reliability and quad-rank architecture ensures that memory performance remains consistent, predictable, and resilient under demanding enterprise workloads.

Enterprise and Data Center Applications

The MEM-DR525PE-ER64 category is tailored for a wide range of enterprise and data center applications. In virtualization environments, these modules support high VM density and improved memory allocation, ensuring predictable performance and minimal latency. Large-scale databases benefit from fast in-memory access and reduced query response times. Cloud infrastructure, AI clusters, and HPC environments gain high-bandwidth, low-latency memory access to support parallel computation and distributed workloads. Mission-critical servers benefit from RDIMM and ECC reliability, ensuring data integrity and system uptime in demanding enterprise operations.

Machine Learning and HPC Workloads

High-capacity DDR5 memory is particularly critical for AI and HPC workloads. The 256GB MEM-DR525PE-ER64 modules provide the bandwidth and memory footprint necessary for large-scale AI model training, scientific simulations, and distributed high-performance computing applications. Multi-node clusters leveraging these modules can handle massive datasets, support parallelized computation, and provide low-latency access for memory-intensive algorithms. The DDR5 6400MHz speed ensures that compute nodes receive data at high rates, improving overall model training times and simulation accuracy.

Data Center and Cloud Infrastructure Applications

In modern data centers, high-performance memory is essential for operational efficiency and SLA compliance. The MEM-DR525PE-ER64 modules enable cloud providers and enterprises to maintain predictable performance across multiple nodes. High-speed DDR5 memory ensures fast provisioning of virtual machines, low-latency web applications, and rapid transaction processing in financial and analytical workloads. Standardized deployment of this memory category simplifies server management, inventory, and scaling across large server farms.

Reliability and Validation

Supermicro validates the MEM-DR525PE-ER64 modules for long-term, continuous operation under enterprise workloads. Modules are tested to ensure low failure rates, thermal stability, and consistent performance in multi-socket, fully populated server configurations. ECC and RDIMM architecture combined with DDR5 speed provide the reliability and error correction necessary for enterprise-grade deployments, ensuring minimal downtime and secure data integrity for mission-critical applications.

Future-Proof DDR5 Memory Investment

Deploying MEM-DR525PE-ER64 modules represents a future-ready investment in DDR5 server memory. Enterprises gain higher bandwidth, lower power consumption, and improved reliability compared to DDR4 memory. With 256GB capacity per DIMM, these modules provide both immediate performance for demanding workloads and the scalability needed for evolving enterprise applications. This memory category ensures compatibility with next-generation server platforms, supporting IT infrastructure growth while maximizing return on investment.

Integration with Advanced Server Chipsets

Modern server chipsets leverage DDR5 memory features, including multi-channel memory access, improved interleaving, and enhanced error detection. MEM-DR525PE-ER64 modules integrate seamlessly with these chipsets, delivering consistent bandwidth, low latency, and predictable system performance. Enterprises deploying these modules in virtualization, cloud, HPC, or AI workloads benefit from balanced memory and CPU performance, optimized for high-density and memory-intensive operations.

Standardization and Deployment

Standardizing on MEM-DR525PE-ER64 modules simplifies server deployment, management, and upgrades. Consistent memory specifications ensure predictable performance, reduce configuration errors, and enable incremental scaling as workloads increase. Enterprises can deploy memory uniformly across multiple nodes, ensuring reliability and minimizing downtime during maintenance or expansion.